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Future Directions and Personalized Longevity Protocols Emerging peptide candidates such as mitochondrial‑derived MOTS‑c and the adipose‑modulating spexin are gaining attention for their ability to boost fatty‑acid oxidation, promote brown‑fat thermogenesis, and suppress adipogenesis, offering a metabolic edge to conventional GH‑releasing peptides

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Research protocols in the published literature have used TB-500 across a range of doses, typically 0.5-2 mg administered subcutaneously in small animal models